| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.02249 | 184 vs 184 | — | Italian | 100 | A-G-G-A-T-A | non A-G-G-A-T-A haplotypes | Candidate Region/Gene | 20126416 |
| rs11568820-rs4516035-rs10735810-rs1544410-rs17878969 | VDR | 11.50 | 0.024 | 104 vs 114 | — | Caucasian, Spaniard | >85 | G-G-C-G-S | non G-G-C-G-S haplotypes | Candidate Region/Gene | 20407924 |
| 9 mtDNA haplogroups | mtDNA haplogroup | 0.38 | 0.025 | 98 vs. 117 | — | Chinese | 90-100 years old | J | non-J | - | 18759861 |
| Haplogroup J | — | 0.38 | 0.025 | 98 vs 117 | — | Chinese | 90–100 | — | — | Candidate Region/Gene | 18759861 |
| rs429358, rs7412 | APOE | — | 0.025 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| rs1061581-rs1043618-rs2227956 | — | 3.46 | 0.025 | 191 vs 53 | — | Chinese | >90 | non A-G-C or non A-C-T haplotypes | A-G-C | Candidate Region/Gene | 19840767 |
| mtDNA haplogroups | mtDNA | — | 0.027 | 138 | — | Spaniard | Minimum age 85 | non-J | J | Mitochondrial Haplogroup | 18931934 |
| 4491A,3705G,10400T | mtDNA | — | 0.027 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs699947-(−1190G/A)-rs1570360-(−634G/C) | VEGFA | — | 0.03 | — | 332 vs 648 | Italian | 85-99 (mean 89.8±2.8) | non A-A-G-G haplotypes | A-A-G-G | Candidate Region/Gene | 17574707 |
| rs2107538-rs2280789 | RANTES | 4.90 | 0.03 | 104 vs 110 | — | Spaniard | Mean age 89.6 | non A-T haplotypes | A-T | Candidate Region/Gene | 22265023 |
| e4 | APOE | 0.55 | 0.03 | 163 vs 1039 | — | Spanish | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| rs1800896 - rs1800629 | IL10 | — | 0.038 | 174 vs 224 | — | Italian | >100 | — | GG-GG (only in men) | Candidate Region/Gene | 12676903 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.03972 | 184 vs 184 | — | Italian | 100 | A-G-G-A | non A-G-G-A haplotypes | Candidate Region/Gene | 20126416 |
| rs2107538-rs2280789 | RANTES | — | 0.04 | 104 vs 110 | — | Spaniard | Mean age 89.6 | non G-C haplotypes | G-C | Candidate Region/Gene | 22265023 |
| e4 | APOE | — | 0.04 | 376 vs 376 | — | Canadian | 85+ | e4 | — | Candidate Region/Gene | 24126160 |
| rs11279109 - APOB XbaI - SI000565Q | APOB | — | 0.044 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - X+ - Short | I - X+ - Medium; D - X- - Long; D - X- - Medium | Candidate Region/Gene | 17393087 |
| LPA isoform | LPA | — | 0.05 | 84 (cases) vs 517 | — | Japanese | 80+ | Lp(a)F, Lp(a)B | — | Candidate Region/Gene | 11269751 |
| D4a | mtDNA haplogroups | — | 0.05 | 112 vs 96 | — | Japanese | Minimum age 105 | non-D4a | D4a | Complete Mitochondrial Genome | 18545700 |
| Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
| rs11279109 - SI000565Q | APOB | — | 0.05 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - S | D - M | Candidate Region/Gene | 17393087 |
| HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
| C4B1 | C4B | — | 0.05 | 77 (cases) vs 235 | — | Italian | Mean age 101 | — | — | Candidate Region/Gene | 10219002 |
| e4 | APOE | 0.41 | 0.05 | 79 vs 597 | — | Italian | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| 12358G,5417A,10873T | mtDNA | — | 0.058 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs1800796-(−373(A)n(T)m)-rs1800795 | IL6 | — | 0.07 | 1710 total | — | Danish | 47-100 | G-(−373(A)8(T)12)-C | non G-(−373(A)8(T)12)-C haplotypes | Candidate Region/Gene | 15130757 |
