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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs2075650 | APOE | 0.53 | 4.44e-16 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs4420638 | APOE | — | 9.6e-08 | 4445 total (each a part of sibship of 2-5 siblings) | — | Caucasian, European | 90 | — | — | Genome-Wide Association Study | 23286790 |
| rs1525501 | — | 0.72 | 4.94e-06 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs3803833 | — | 0.77 | 2.72e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs1016013 | — | 1.21 | 2.87e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs11218921 | — | 0.59 | 5.47e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs216148 | CSF1R | 0.75 | 6.36e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs2738679 | WWOX | 1.60 | 6.85e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs1867102 | C9orf3 | 1.20 | 7.28e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs1822590 | — | 1.21 | 7.57e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs17702471 | GPC6 | 1.81 | 8.33e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs1042663 | C2 | 0.72 | 8.39e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs4918255 | SORCS1 | 1.21 | 8.81e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs1456669 | — | 0.78 | 9.89e-05 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs915179 | LMNA | 1.19 | 0.0001 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs2738173 | DEFB1 | 0.78 | 0.00016 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs651922 | DCPS | 1.65 | 0.00018 | 2202 vs 2164 | — | Caucasian | 100 | — | — | Meta-Analysis | 24244950 |
| rs4952085 | XDH | 1.25 | 0.000933537 | 801 vs 914 | — | Caucasian | Median age 104 | A | G | Genome-Wide Association Study | 22279548 |
| rs508641 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs1800624 | — | — | 0.028 | 28 vs 56 | — | Caucasian | 90+ | non-AA | AA | Candidate Region/Gene | 24284407 |
| rs1801282 | PPARG | — | 0.035 | 222 vs 250 | — | Caucasian | 86 to 109; median age 99 | G | — | Candidate Region/Gene | 15236769 |
| rs1805097 | IRS2 | 2.07 | 0.04 | 144 vs 418 | — | Caucasian | 85 to 104, mean age = 96 ± 4 | C | — | Candidate Region/Gene | 19887537 |