Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2738173 DEFB1 0.78 0.00016 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1525501 — 0.81 8.97e-05 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs1456669 — 0.82 0.000312 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs4729049 CDK6 1.21 0.001311 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs11954180 SLC6A7 1.30 0.001639 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs2596230 RYR3 2.61 0.000383 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs1800392 WRN 0.79 0.000708 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579
rs1799752 ACE 1.25 0.032 1803 vs 10484 — Multiethnic Centenarian — DD Meta-Analysis 23623925
rs1799752 ACE 1.16 0.001 1803 vs 10484 — Multiethnic Centenarian — D Meta-Analysis 23623925
rs1800591 MTTP — 0.64 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701
rs61733139 MTTP — 0.43 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701
rs1800591-rs61733139 MTTP — 0.46 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701