Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2802288 FOXO3A 1.24 0.003 1688 vs 1214 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2802292 FOXO3A 1.36 0.005 2521 vs 2537 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2764264 FOXO3A 1.20 0.01 1959 vs 1621 — Multiethnic 90+ — — Meta-Analysis 25038186
rs1799752 ACE 1.25 0.032 1803 vs 10484 — Multiethnic Centenarian — DD Meta-Analysis 23623925
rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579
rs61733139 MTTP — 0.43 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701
rs1800591-rs61733139 MTTP — 0.46 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701
rs708272 CETP — 0.53 — — Multiethnic — — — Meta-Analysis 24468472
rs5882 CETP — 0.63 — — Multiethnic — — — Meta-Analysis 24468472
rs1800591 MTTP — 0.64 655 vs 244 — Dutch Mean age 87.5±3.1 — — Meta-Analysis 16611701
rs2153960 FOXO3A — 1.0 1435 vs 2098 — Multiethnic 90+ — — Meta-Analysis 25038186
rs7762395 FOXO3A — 1.0 2832 vs 2168 — Multiethnic 90+ — — Meta-Analysis 25038186
rs13220810 FOXO3A — 1.0 1746 vs 1219 — Multiethnic 90+ — — Meta-Analysis 25038186