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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| HRAS1 LASS1 (CCT) | APOE | — | 4.1e-05 | 147 vs 188 | — | Georgian | — | — | — | Candidate Region/Gene | 20569235 |
| rs12050077 | TSHR | 1.68 | 0.0001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | G | A | Candidate Region/Gene | 19837933 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | C | Candidate Region/Gene | 22406557 |
| rs2267723 | GHRHR | 0.70 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs3842755 | INS | 1.79 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | C | A | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs3842755 | INS | 1.79 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | C | — | Candidate Region/Gene | 22406557 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | A | — | Candidate Region/Gene | 22406557 |
| rs2267723 | GHRHR | 0.70 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | G | — | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | A | — | Candidate Region/Gene | 22406557 |
| rs4746720 | SIRT1 | 2.10 | 0.0001 | 223 vs 277 | — | Chinese | Average age 93 | CC, TT | CT | Candidate Region/Gene | 23450480 |
| rs13251813 | WRN | 1.84 | 0.0002 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs8052394 | MT1a | 2.16 | 0.0002 | 151 vs 100 | — | Italian | Mean age 91.4 +/- 4.1 | — | A | Candidate Region/Gene | 16955215 |
| rs3800231 | FOXO3 | 1.42 | 0.0002 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs1800896 | IL10 | 3.10 | 0.0003 | 142 vs 153 | — | Mean age 67 | AA | GG | Candidate Region/Gene | 15466015 | |
| rs2075650 | APOE | — | 0.000527 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | T | Candidate Region/Gene | 22445811 |
| rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs429358, rs7412 | APOE | 0.43 | 0.0006 | 114 vs 2071 | — | Irish | >90 | e4 | e2 | Candidate Region/Gene | 11470126 |
| rs9400239 | FOXO3 | 1.38 | 0.0007 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs5882 | CETP | 3.56 | 0.001 | 213 vs 258 | — | Ashkenazi Jewish | 98,2 +/- 5,3 | non-GG | GG | Candidate Region/Gene | 14559957 |
| rs1333049 | — | 0.64 | 0.001 | 80 (cases) vs 258 healthy young | — | Human | 100–104 | C | — | Candidate Region/Gene | 20230275 |
| K153R | MSTN | 3.48 | 0.001 | 156 vs 384 | 79 vs 316 | Italian, Spaniard | 100–111 | K | — | Candidate Region/Gene | 23354683 |
| rs10149689 | TSHR | 1.56 | 0.001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | A | G | Candidate Region/Gene | 19837933 |
| rs978739 | TAS2R16 | 0.62 | 0.001 | 348 vs 593 | — | Calabrian | Mean age 93.82 | non-AA | AA | Candidate Region/Gene | 23133589 |
| rs479744 | FOXO3 | 1.40 | 0.001 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |