| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs4537545 | IL6R | — | 3e-18 | 308 | — | American, European, Ashkenazi Jewish | 75.7 | — | — | Candidate Region/Gene | 19249341 |
| HRAS1 LASS1 (CGT) | APOE | — | 1.06e-09 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 6.91e-07 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 1e-06 | 79 vs 88 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| HRAS1 LASS1 (CCT) | APOE | — | 9.5e-05 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| rs429358, rs7412 | APOE | — | 0.0005 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | e4 | e2 | Candidate Region/Gene | 18034366 |
| rs2075650 | APOE | — | 0.000527 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | T | Candidate Region/Gene | 22445811 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.00197 | 125 vs 163 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| rs2075650 | TOMM40 | 0.70 | 0.002 | 2307 vs 764 | — | American, Danish | Mean age 60.2 | G | A | Candidate Region/Gene | 23040522 |
| −438 G/A | TAFI | 0.53 | 0.003 | 2224 | — | American, Caucasian | 65+ | G (men) | — | Candidate Region/Gene | 15939070 |
| apoE haplotypes | — | — | 0.0042 | 3924 | — | American | 5-70 | Apo e4 | — | Candidate Region/Gene | 21332925 |
| rs429358, rs7412 | APOE | 0.75 | 0.005 | 2307 vs 764 | — | American, Danish | Mean age 60.2 | e4 | e2 | Candidate Region/Gene | 23040522 |
| rs508641 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs2866164 | MTP | — | 0.024 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | GG | — | Candidate Region/Gene | 18034366 |
| −675 4G/5G | PAI1 | 0.81 | 0.04 | 2224 | — | American, Caucasian | 65+ | 5G (men) | — | Candidate Region/Gene | 15939070 |
| rs6669212 | LMNA | — | 0.041 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs5882 | CETP | 1.30 | 0.041 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100.8 | non-GG | GG | Candidate Region/Gene | 18034366 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.0511 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| rs1468772 | LMNA | 1.17 | 0.054 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs582690 | LMNA | — | 0.078 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs547915 | LMNA | — | 0.11 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
