Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
- Insulin signaling pathway (IIS) — 0.01 403 vs 1670 — European 90-103 — — Genome-Wide Association Study 22113349
- Telomere maintenance pathway (TM) — 0.02 403 vs 1670 — European 90-103 — — Genome-Wide Association Study 22113349
3p24-22 3p24-22 — 0.037 3953 — American Minimum age 98 — — Genome-Wide Association Study 20824210
marker D4S1564 — — 0.044 308 — European min. age 98 for one sibling. 91+ males, 95+ females — — Genome-Wide Association Study 11526246
rs326146 ADCY2 1.46 0.024 137 vs 213 — Korean Mean age 90 — A Genome-Wide Association Study 19641380
rs155979 PCSK1 0.61 0.012 137 vs 213 — Korean Mean age 90 G — Genome-Wide Association Study 19641380
rs3811952, rs155979, rs3762985 — 0.54 0.008 137 vs 213 — Korean Mean age 90 CGA — Genome-Wide Association Study 19641380
rs4237973 PIK3C2G 1.51 0.022 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
rs1800802 MGP 0.77 0.132 137 vs 213 — Korean Mean age 90 C — Genome-Wide Association Study 19641380
rs1054016 TNFSF11 1.09 0.579 137 vs 213 — Korean Mean age 90 T — Genome-Wide Association Study 19641380
rs327519 PAX4 (for males) 5.70 0.004 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
rs712700 — 1.87 0.01 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
rs327512 — 5.55 0.005 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
rs1980042 LYN (for males) 2.10 0.006 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
rs1979128 — 2.10 0.006 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
rs1450740, rs1450741, rs1562818, rs1980042, rs1027989, rs 1546518, rs3968371 — 3.72 0.002 137 vs 213 — Korean Mean age 90 — CTCCGCA Genome-Wide Association Study 19641380
rs2274471 JAK2 (for males) 1.58 0.088 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
rs671 ALDH2 (for males) 2.11 0.009 137 vs 213 — Korean Mean age 90 — A Genome-Wide Association Study 19641380
rs2030071 IL12RB2 (for females) 0.18 0.008 137 vs 213 — Korean Mean age 90 T — Genome-Wide Association Study 19641380
rs2072454, rs2293347, rs3807362, rs884225 EGFR (for females) 4.11 0.003 137 vs 213 — Korean Mean age 90 — CGCA Genome-Wide Association Study 19641380
rs3800358 BTBD9 — 0.00541 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs1974676 Intergenic — 0.00496 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
rs1834497 CLSTN2 — 0.00979 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs2590504 KIAA0649 — 0.00854 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs2024714 CDH4 — 7.43e-05 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
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  • 25 of 710 variants