Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
- Insulin signaling pathway (IIS) — 0.01 403 vs 1670 — European 90-103 — — Genome-Wide Association Study 22113349
- Telomere maintenance pathway (TM) — 0.02 403 vs 1670 — European 90-103 — — Genome-Wide Association Study 22113349
rs9330200 TUBB4B — 6e-53 5036 — American 28-70 AA, AT TT Genome-Wide Association Study 22174011
rs2292664 RIMBP2 — 1.4e-37 5036 — American 28-70 CC, CG GG Genome-Wide Association Study 22174011
rs5491 ICAM1 — 5e-66 5036 — American 28-70 TT, AT AA Genome-Wide Association Study 22174011
Chromosome 4 at D4S1564 Chromosome 4 at D4S1564 — 0.044 303 — Human Minimum age 98 for one sibling (of sibship) — — Genome-Wide Association Study 11526246
3p24-22 3p24-22 — 0.037 3953 — American Minimum age 98 — — Genome-Wide Association Study 20824210
rs2802292 FOXO3A — 1.0 403 vs 1670 4149 vs 7582 Dutch mean 94 — — Genome-Wide Association Study 21418511
marker D4S1564 — — 0.044 308 — European min. age 98 for one sibling. 91+ males, 95+ females — — Genome-Wide Association Study 11526246
3p24.2–22.3 — — 0.037 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
9q31.3–34.2 — — 0.054 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
rs4420638 APOE — 9.6e-08 4445 total (each a part of sibship of 2-5 siblings) — Caucasian, European 90 — — Genome-Wide Association Study 23286790
rs3800358 BTBD9 — 0.00541 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs1974676 Intergenic — 0.00496 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
rs1834497 CLSTN2 — 0.00979 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs2590504 KIAA0649 — 0.00854 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs2024714 CDH4 — 7.43e-05 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs41383 NLRC5 — 0.00455 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs16975963 Noncoding — 0.00713 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
rs13008689 Intergenic — 0.00686 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs3120819 Intergenic — 0.00806 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs9876781 Noncoding — 0.000868 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs9517320 STK24 — 0.00204 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs139170 PARVG — 0.00332 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs4648884 RUNX3 — 0.00992 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
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  • 25 of 710 variants