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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
apoE haplotypes 0.0042 3924 American 5-70 Apo e4 Candidate Region/Gene 21332925
3p24-22 3p24-22 0.037 3953 American Minimum age 98 Genome-Wide Association Study 20824210
rs2075650 APOE 0.000527 1364 American, British Age range 50-108; mean age at death 80.2 C T Candidate Region/Gene 22445811
rs3764650 ABCA7 0.135 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs610932 MS4A6A 0.176 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs3851179 PICALM 0.227 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs11767557 EPHA1 0.267 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs3865444 CD33 0.442 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs3818361 CR1 0.563 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs1485780 CD2AP 0.604 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs744373 BIN1 0.689 1364 American, British Age range 50-108; mean age at death 80.2 A G Candidate Region/Gene 22445811
rs11136000 CLU 0.975 1364 American, British Age range 50-108; mean age at death 80.2 A G Candidate Region/Gene 22445811
rs987839 SLCO1B1 3.19e-06 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
rs17205854 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
rs17811551 ADAMTS6 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
rs1857821 NAAA 5.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
rs7525717 5.76e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
rs4673651 ERBB4 6.08e-06 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
rs17049647 7.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
rs10518142 NAAA 8.89e-06 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
rs2444861 C8orf47 8.99e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
rs1418425 9.64e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
rs2271528 SDAD1 1.02e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
rs1555453 MOBKL2B 1.07e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
rs13111494 ART3 1.28e-05 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
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  • 25 of 303 variants