polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90+ | apoE4 | — | Candidate Region/Gene | 11780357 |
LPA isoform | LPA | — | 0.05 | 84 (cases) vs 517 | — | Japanese | 80+ | Lp(a)F, Lp(a)B | — | Candidate Region/Gene | 11269751 |
apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | ApT4 | Candidate Region/Gene | 11780357 |
apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | — | Candidate Region/Gene | 11780357 |
D4a | mtDNA haplogroups | — | 0.05 | 112 vs 96 | — | Japanese | Minimum age 105 | non-D4a | D4a | Complete Mitochondrial Genome | 18545700 |
Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
APOE polymorphism | APOE | — | 0.0001 | 291 vs 589 | — | Finn | Mean age 97.5 | e4 | e2 | Candidate Region/Gene | 16487435 |
rs1800896 - rs1800629 | IL10 | — | 0.038 | 174 vs 224 | — | Italian | >100 | — | GG-GG (only in men) | Candidate Region/Gene | 12676903 |
mtDNA haplogroups | mtDNA | — | 0.027 | 138 | — | Spaniard | Minimum age 85 | non-J | J | Mitochondrial Haplogroup | 18931934 |
rs1800591-rs61733139 | MTTP | — | 0.61 | 197 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
rs1800591-rs61733139 | MTTP | — | 0.46 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
rs2234693 - rs2234693 | ESR1 | — | 0.12 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
APOE haplotype - rs1346044 | APOE | — | 0.0001 | 175 vs 178 | — | Finn | 100.8 | e4 | e2 | Candidate Region/Gene | 10069711 |
APOE polymorphism | APOE | — | 0.437 | 1408 cases | — | Brazilian | 69.3 +/- 7.2 | — | — | Candidate Region/Gene | 17934638 |
rs11279109 - APOB XbaI | APOB | — | 0.001 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | — | D - X+ | Candidate Region/Gene | 17393087 |
APOB XbaI − SI000565Q | APOB | — | 0.006 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | X+ - Short | X+ - Medium | Candidate Region/Gene | 17393087 |
rs11279109 - SI000565Q | APOB | — | 0.05 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - S | D - M | Candidate Region/Gene | 17393087 |
rs11279109 - APOB XbaI - SI000565Q | APOB | — | 0.044 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - X+ - Short | I - X+ - Medium; D - X- - Long; D - X- - Medium | Candidate Region/Gene | 17393087 |
APOE polymorphism - HP1/2 common polymorphism | APOE | — | 0.013 | 200 (cases) vs 539 (initial) | — | Italian | >88 | e4-H2 (haplotype) | — | Candidate Region/Gene | 21703254 |
HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
5178A,10400T | mtDNA | — | 0.387 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
3010A,5178A,10400T | mtDNA | — | 0.141 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
14979C,3010A,5178A,10400T | mtDNA | — | 0.781 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
8020A,3010A,5178A,10400T | mtDNA | — | 0.549 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
8964T,8020A,3010A,5178A,10400T | mtDNA | — | 0.319 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |