| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs2542052 | APOC3 | — | 0.0001 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | Mean age 98.2 | A | — | — | 16602826 |
| rs5882 | CETP | — | 0.069 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | Mean age 98.2 | A | — | — | 16602826 |
| mt146 C>T | — | — | 0.005 | 113 (cases) vs 200 | — | Chinese | 90-110 | mt146T | mt146C | Complete Mitochondrial Genome | 22729909 |
| rs2476601 | PTPN22 | — | 0.663 | 225 vs 278 | — | Italian | Mean age 93 | — | — | Candidate Region/Gene | 21113673 |
| rs1801133 | MTHFR | — | 0.01 | 108 (patients with CVD) vs 118 | — | Swiss | >65 | C | — | Candidate Region/Gene | 10583447 |
| rs5882 | CETP | — | 0.318 | 175 vs 189 | — | Italian | 99.6 | — | — | Candidate Region/Gene | 15888337 |
| rs2069827 | IL6 | — | 0.064 | 1,089 vs 736 | 563 (longtitudinal study) | Danish, Dutch | 92+ Danish, 85+ Dutch | A | — | — | 22234866 |
| rs2282679 | GC | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
| rs132793 | XRCC6 | — | 0.74 | 224 vs 293 | 170 vs 220 | Caucasian, European | 90-103, 98+ (replication) | — | — | Candidate Region/Gene | 21972126 |
| rs2234693 | ESR1 | — | 0.08 | 108 vs 85 | — | Italian | 90+ | PP (genotype) | — | Candidate Region/Gene | 20819792 |
| rs1800795 | IL6 | — | 0.006 | 244 vs 309 | 138 vs 98 | Italian | 85+ | CC (genotype) | — | Candidate Region/Gene | 19377912 |
| rs1937 | TFAM | — | 0.003 | 107 vs 284 | — | Spaniard | 100–111 | G | CC (genotype) | Candidate Region/Gene | 23186209 |
| rs708272 | CETP | — | 0.068 | 523 vs 498 | — | Chinese | Mean age 93.4 | — | — | Candidate Region/Gene | 22336474 |
| rs6457452 | HSP70-A1B | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| rs5882 | CETP | — | 0.05 | 300 vs 320 vs 258 | — | Ashkenazi Jewish | Minimum age 95 | AA, AG | GG | Candidate Region/Gene | 15621216 |
| rs1799782 | XRCC1 | — | 0.658 | 430 vs 290 | — | British | Mean age 70 | — | — | Candidate Region/Gene | 16518718 |
| rs25487 | XRCC1 | — | 0.51 | 430 vs 290 | — | British | Mean age 70 | — | — | Candidate Region/Gene | 16518718 |
| rs861539 | XRCC3 | — | 0.97 | 430 vs 290 | — | British | Mean age 70 | — | — | Candidate Region/Gene | 16518718 |
| rs28360135 | XRCC4 | — | 0.29 | 430 vs 290 | — | British | Mean age 70 | — | — | Candidate Region/Gene | 16518718 |
| rs9330200 | TUBB4B | — | 6e-53 | 5036 | — | American | 28-70 | AA, AT | TT | Genome-Wide Association Study | 22174011 |
| rs2292664 | RIMBP2 | — | 1.4e-37 | 5036 | — | American | 28-70 | CC, CG | GG | Genome-Wide Association Study | 22174011 |
| rs5491 | ICAM1 | — | 5e-66 | 5036 | — | American | 28-70 | TT, AT | AA | Genome-Wide Association Study | 22174011 |
| rs1800896 | IL10 | — | 0.019 | 174 vs 227 | — | Italian | >100 | — | GG | Candidate Region/Gene | 12676903 |
| rs1799945 | HFE | — | 0.008 | 57 vs 60 | — | Italian | 100-105 | — | — | Candidate Region/Gene | 12714263 |
| rs4880 | SOD2 | — | 0.009 | 224 vs 441 | — | Ashkenazi Jewish | 75 | C | T | Candidate Region/Gene | 15621215 |
