Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2305268 PIK3CB — 0.363 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs3745544 INSR — 0.441 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs8192678 PPARGC1A — 0.469 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2297627 FOXO1A — 0.495 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs3736265 PPARGC1A — 0.509 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2297626 FOXO1A — 0.512 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs1801123 IRS1 — 0.774 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs361072 PIK3CB — 0.829 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
LPA isoform LPA — 0.05 84 (cases) vs 517 — Japanese 80+ Lp(a)F, Lp(a)B — Candidate Region/Gene 11269751
rs3751436 FOXO1A — 0.369 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
1/s 5HTT — 0.05 265 vs 225 — Japanese 101.2 S — Candidate Region/Gene 16095668
D4a mtDNA haplogroups — 0.05 112 vs 96 — Japanese Minimum age 105 non-D4a D4a Complete Mitochondrial Genome 18545700
82133GNA PLXNA1 — 0.0189 26 vs 27 — Japanese 60-69, 90-99, >100 — — — 15820493
rs7843014 PTK2 — 1.0 742 vs 499 — Japanese 100-116 — — Candidate Region/Gene 24930376
rs7460 PTK2 — 1.0 742 vs 499 — Japanese 100-116 — — Candidate Region/Gene 24930376
rs1333049 CDKN2B-AS1 — 0.602 742 vs 920 — Japanese 100 — — Candidate Region/Gene 24163049
rs6519194 ATF4 — 0.41 206 vs 397 — Japanese 95+ — — Candidate Region/Gene 23770741
rs738288 ATF4 — 0.54 205 vs 396 — Japanese 95+ — — Candidate Region/Gene 23770741
rs12786104 CBL — 0.12 210 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
rs11217184 CBL — 0.8 212 vs 396 — Japanese 95+ — — Candidate Region/Gene 23770741
rs2249466 CBL — 0.9 207 vs 394 — Japanese 95+ — — Candidate Region/Gene 23770741
rs7914 CBL — 0.69 190 vs 376 — Japanese 95+ — — Candidate Region/Gene 23770741
rs2511837 CBL — 0.14 212 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1776180 EXO1 — 0.16 206 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1815274 JUN — 0.18 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741