| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| Q/H 95, rs2866164 | — | — | 0.0005 | 653 (197 m, 456 f) vs non-mentioned | 564 (92 m, 472 f) vs 564___(Franch Caucasians) | American, Caucasian | Mean 100,8 | Q95 G | — | Genome-Wide Association Study | 14615589 |
| rs1553432 | Intergenic (upstream of C4orf17) | — | 0.0005 | 653 (197 m, 456 f) vs non-mentioned | 564 (92 m, 472 f) vs 564___(Franch Caucasians) | American, Caucasian | Mean 100,8 | — | — | Genome-Wide Association Study | 14615589 |
| rs429358, rs7412 | APOE | — | 0.0005 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | e4 | e2 | Candidate Region/Gene | 18034366 |
| rs750032 | PPP3CA | — | 0.0029 | 653 (197 m, 456 f) vs non-mentioned | 564 (92 m, 472 f) vs 564___(Franch Caucasians) | American, Caucasian | Mean 100,8 | — | — | Genome-Wide Association Study | 14615589 |
| −438 G/A | TAFI | 0.53 | 0.003 | 2224 | — | American, Caucasian | 65+ | G (men) | — | Candidate Region/Gene | 15939070 |
| rs951085 | Intergenic | — | 0.0041 | 653 (197 m, 456 f) vs non-mentioned | 564 (92 m, 472 f) vs 564___(Franch Caucasians) | American, Caucasian | Mean 100,8 | — | — | Genome-Wide Association Study | 14615589 |
| rs752766 | Intergenic | — | 0.0058 | 653 (197 m, 456 f) vs non-mentioned | 564 (92 m, 472 f) vs 564___(Franch Caucasians) | American, Caucasian | Mean 100,8 | — | — | Genome-Wide Association Study | 14615589 |
| rs508641 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs2866164 | MTP | — | 0.024 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | GG | — | Candidate Region/Gene | 18034366 |
| −675 4G/5G | PAI1 | 0.81 | 0.04 | 2224 | — | American, Caucasian | 65+ | 5G (men) | — | Candidate Region/Gene | 15939070 |
| rs6669212 | LMNA | — | 0.041 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs5882 | CETP | 1.30 | 0.041 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100.8 | non-GG | GG | Candidate Region/Gene | 18034366 |
| rs1468772 | LMNA | 1.17 | 0.054 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs582690 | LMNA | — | 0.078 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs547915 | LMNA | — | 0.11 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs10737170 | LMNA | — | 0.11 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs4661146 | LMNA | — | 0.12 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs12117552 | LMNA | — | 0.21 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs12063072 | LMNA | — | 0.36 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs4641 | LMNA | — | 0.5 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs6686943 | LMNA | — | 0.51 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
