Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs10514626 — 0.38 1.12e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs7873259 ANKRD19 3.14 1.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs16947526 — 0.56 1.23e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs10496799 NXPH2 — 1.4e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs11790055 — 1.38 1.49e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs12088486 — 0.56 1.75e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs10959258 — 1.36 1.86e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs6769400 — 1.91 1.99e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs6689491 — — 2e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs9595687 — 0.49 2.09e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs11237644 — 1.52 2.11e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs4938180 IGSF4 1.91 2.16e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs2147556 — 0.63 2.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs10493515 — — 2.3e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs1563301 — 0.50 2.36e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs6592810 — 1.54 2.49e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs571391 IMPG2 0.55 2.67e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs7915479 CDH23 1.92 2.81e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs870959 — 1.51 2.84e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs1556758 SORCS1 0.50 3.47e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs130329 — 0.50 3.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs10489006 — — 3.6e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs10493518 — — 3.6e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs846427 — 1.94 3.82e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs10277343 — 0.64 3.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516