| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs4420638 | APOC1 | 0.53 | 1.8e-10 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | G | — | Genome-Wide Association Study | 21740922 |
| rs3800231 | FOXO3 | 1.42 | 0.0002 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs9400239 | FOXO3 | 1.38 | 0.0007 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs479744 | FOXO3 | 1.40 | 0.001 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs770087 | DUSP6 | 1.53 | 0.002 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
| rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| C4L*Q0 | — | — | 0.003 | 700 vs 900 | — | German | 94+ | — | — | Candidate Region/Gene | 24465950 |
| rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs7762395 | FOXO3 | 1.38 | 0.005 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs11040489 | KRTAP5-6 | — | 0.005869 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs6911407 | FOXO3 | 1.28 | 0.006 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs2802288 | FOXO3 | 1.28 | 0.006 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs768023 | FOXO3 | 1.27 | 0.007 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs2802290 | FOXO3 | 1.26 | 0.01 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs4930001 | DEAF1 | — | 0.010851 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs2301582 | NALP1 | 1.30 | 0.011 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
| rs648802 | PERP | 1.29 | 0.012 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
| rs769449 | APOE | 0.70 | 0.018 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | G | — | — | 22234866 |
| rs13220810 | FOXO3 | 0.78 | 0.02 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs1268170 | FOXO3 | 1.24 | 0.02 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs11188059 | CYP2C | — | 0.04 | 616 centenarians versus control group of 945 younger individuals | — | German | — | — | — | Candidate Region/Gene | 21798861 |
| rs473268 | FOXO3 | 1.21 | 0.044 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
| rs12200646 | FOXO3 | 1.28 | 0.064 | 388 vs 371 | 535 vs 553 | German | mean age 98.4 years | — | — | Candidate Region/Gene | 19196970 |
