Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated « 
  • Study type: + -
    Meta‑Analysis « 
  • Variant type: + -
    SNP (30)  
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    Populations | Study Types | Variant Types


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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs2802288 FOXO3A 1.24 0.003 1688 vs 1214 — Multiethnic 90+ — — Meta-Analysis 25038186
    rs2802292 FOXO3A 1.36 0.005 2521 vs 2537 — Multiethnic 90+ — — Meta-Analysis 25038186
    rs2764264 FOXO3A 1.20 0.01 1959 vs 1621 — Multiethnic 90+ — — Meta-Analysis 25038186
    rs1799752 ACE 1.25 0.032 1803 vs 10484 — Multiethnic Centenarian — DD Meta-Analysis 23623925
    rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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