Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
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    ‑ (19)   Candidate Region/Gene (382)   Meta‑Analysis (8)   Genome‑Wide Association Study (103)   Mitochondrial Haplogroup (27)  
  • Variant type: + -
    SNP (314)   Haplotype (43)   Other (1)   STR (7)   Deletion (1)  
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    HRAS1 LASS1 (CCT) APOE — 4.1e-05 147 vs 188 — Georgian — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE — 7.8e-05 147 vs 188 — Georgian — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CCT) APOE — 9.5e-05 204 vs 251 — American — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE — 6.91e-07 204 vs 251 — American — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CCT) APOE — 1e-05 128 vs 115 — Georgian — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE — 9e-06 19 vs 73 — Georgian — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CCT) APOE — 0.00197 125 vs 163 — American — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE — 1e-06 79 vs 88 — American — — — Candidate Region/Gene 20569235
    HRAS1 LASS1 (CCT) APOE — 0.0511 68 vs 68 — American — — — Candidate Region/Gene 20569235
    R353Q FVII — 0.61 113 vs 100 — Scottish 96 years vs 32 years — — - 10744171
    microsatellite polymorphism surrounded by rs2288377, rs5742612, and rs35767 IGF1 — 0.922 493 vs 425 — Chinese (females ≥ 94; males ≥ 90 — — Candidate Region/Gene 20199671
    length (STR polymorphism) TH — 1.0 196 vs 358 471 vs 462 German (in replication) 96-110 years — — Candidate Region/Gene 21407269
    rs6457931 CDKN1A 1.01 0.936 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs1321312 CDKN1A 0.75 0.181 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs4331968 CDKN1A 1.09 0.655 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs9470367 CDKN1A 1.01 0.949 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs6920453 CDKN1A 1.13 0.537 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs9462209 CDKN1A 1.25 0.228 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs4713999 CDKN1A 0.83 0.295 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs1321309 CDKN1A 1.18 0.326 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs4711459 CDKN1A 1.11 0.655 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs4711461 CDKN1A 1.24 0.364 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs4714003 CDKN1A 0.92 0.789 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    SNP at chromosome location 36750804 CDKN1A 0.83 0.414 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs10947623 CDKN1A 1.37 0.199 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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