Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (243)   No Age Effect (314)  
  • Study type: + -
    GWAS (2)   ‑ (1)   Candidate Region/Gene (375)   Meta‑Analysis (37)   Complete Mitochondrial Genome (1)   Genome‑Wide Association Study (147)   Mitochondrial Haplogroup (1)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP « 
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    73G — — 0.0086 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
    152C — — 0.004 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
    8899A — — 0.0016 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
    mt9055A mtDNA — 0.164 129 vs 100 — Irish 80-97 — — Mitochondrial Haplogroup 11404057
    rs135416 — 0.57 8.65e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs130329 — 0.50 3.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2070325 LPLUNC4 2.42 5.98e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6504441 PRKCA 0.60 2.87e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2967137 — 1.83 4.64e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1582594 — 1.87 4.76e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs81647 — 0.58 9.77e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4777170 — 2.00 4.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10134056 — 0.46 5.61e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2277472 MAMDC1 1.95 7.93e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4594173 MADMC1 1.94 9.81e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1584547 — 2.96 8.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs285097 RNF113B 0.47 7.76e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs731287 — 2.51 9.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2147556 — 0.63 2.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs9315385 DCAMKL1 1.74 8.13e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs969845 — 5.87 7.22e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2111173 PTPRO 1.74 9.24e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4938180 IGSF4 1.91 2.16e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6592810 — 1.54 2.49e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs870959 — 1.51 2.84e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    • Page 1 of 23
    • 25 of 572 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue