Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

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    SNP (97)  
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    Populations | Study Types | Variant Types


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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs2802292 FOXO3A — 1.0 403 vs 1670 4149 vs 7582 Dutch mean 94 — — Genome-Wide Association Study 21418511
    rs1054016 TNFSF11 1.09 0.579 137 vs 213 — Korean Mean age 90 T — Genome-Wide Association Study 19641380
    (rs429358, rs7412) + (rs2075650) APOE + TOMM40 0.93 0.337 403 vs 1670 3746 vs 5912 Dutch Mean age 94 e4 + G — Genome-Wide Association Study 21418511
    rs1800802 MGP 0.77 0.132 137 vs 213 — Korean Mean age 90 C — Genome-Wide Association Study 19641380
    rs2274471 JAK2 (for males) 1.58 0.088 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
    9q31.3–34.2 — — 0.054 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
    3p24.2–22.3 — — 0.037 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
    rs6459623 IBRDC2 — 0.00015 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs1405051 — — 0.00014 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs1915501 — — 0.00011 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs712773 GRM7 0.66 9.99e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs731287 — 2.51 9.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4594173 MADMC1 1.94 9.81e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs81647 — 0.58 9.77e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs3134204 — 1.51 9.71e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2111173 PTPRO 1.74 9.24e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs3102484 — 1.82 9.2e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6540664 — 1.46 9e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs697739 ATXN1 0.59 8.97e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs9366292 — 0.64 8.65e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs135416 — 0.57 8.65e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1584547 — 2.96 8.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4505466 SH3BP4 2.06 8.31e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10498263 OR4Q3 — 8.3e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs2073586 ABCC8 0.48 8.15e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    • Page 1 of 5
    • 25 of 103 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue