Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (50)   No Age Effect (97)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP « 
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs9330200 TUBB4B — 6e-53 5036 — American 28-70 AA, AT TT Genome-Wide Association Study 22174011
    rs17049647 — — 7.12e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs10518142 NAAA — 8.89e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs2271528 SDAD1 — 1.02e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs3210458 ACPL2 — 1.52e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs7803143 PSCD3 — 1.57e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs7622678 BDH1 — 1.93e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs10901296 ABL1 — 2.37e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs1537438 — — 2.53e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs6454676 — — 2.9e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs17047650 FAM19A1 — 3.19e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs10433502 FAM19A1 — 3.49e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs3125524 — — 3.83e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs2292664 RIMBP2 — 1.4e-37 5036 — American 28-70 CC, CG GG Genome-Wide Association Study 22174011
    rs970048 Intergenic 1.77 7.17e-07 3746 vs 5912 — Dutch Mean age 94 — G Genome-Wide Association Study 21418511
    rs4952085 XDH 1.25 0.000933537 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1857821 NAAA — 5.12e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs7525717 — — 5.76e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs2444861 C8orf47 — 8.99e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs1418425 — — 9.64e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs13111494 ART3 — 1.28e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs4720752 RPA3 — 1.93e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs4280854 — — 3.85e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs7103504 CNTN5 — 4.39e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs7952321 OR5AS1 — 4.68e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T G Genome-Wide Association Study 22445811
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    • 25 of 147 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue