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Denigma
»
Lifespan
»
Variants
» Variant = rs2229765
o
|
Admin
Mouse Lifespan Experiments
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rs2229765
Polymorphism:
rs2229765
rs2229765
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
12q23.2
Factor:
- Symbol:
IGF-1
- Name:
insulin-like growth factor 1 (somatomedin C)
- Entrez ID:
3479
- Ensembl ID:
ENSG00000017427
Factors:
IGF-1
insulin-like growth factor 1 (somatomedin C)
(
3479
/
ENSG00000017427
)
Description:
Significant only in males.
Ethnicity:
Italian
Age of cases:
>85
Shorter lived allele:
G
Longer lived allele:
A
Finding:
Positive
Statistics
- Number of cases/controls:
222 vs 288 (initial)
- Odds ratio type:
Longer
- p-value:
0.04 [0.04]
- Significant:
yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
PCR
Reference:
19460140: A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study.
Choice:
Clean
Created:
July 2, 2013, 2:47 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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