Polymorphism: rs2229765
rs2229765 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 12q23.2

Factor:
- Symbol: IGF-1
- Name: insulin-like growth factor 1 (somatomedin C)
- Entrez ID: 3479
- Ensembl ID: ENSG00000017427

Factors:
  • IGF-1 insulin-like growth factor 1 (somatomedin C) ( 3479 / ENSG00000017427 )


  • Description:

    Significant only in males.

    Ethnicity: Italian
    Age of cases: >85
    Shorter lived allele: G
    Longer lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 222 vs 288 (initial)
    - Odds ratio type: Longer
    - p-value: 0.04 [0.04]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    19460140: A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study.

    Choice: Clean
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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