Polymorphism: rs2229765
rs2229765
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 12q23.2
Factor:
- Symbol: IGF-1
- Name: insulin-like growth factor 1 (somatomedin C)
- Entrez ID: 3479
- Ensembl ID: ENSG00000017427
Factors:
IGF-1
insulin-like growth factor 1 (somatomedin C)
(
3479
/
ENSG00000017427
)
Description:
Significant only in males.
Ethnicity:
Italian
Age of cases: >85
Shorter lived allele: G
Longer lived allele: A
Finding: Positive
Statistics
- Number of cases/controls: 222 vs 288 (initial)
- Odds ratio type: Longer
- p-value:
0.04
[0.04]
- Significant: yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
19460140: A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study.
Choice: Clean
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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