| zyg-11 RNAi | zyg-11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| ZC395.10 RNAi | ZC395.10 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| Y41E3.11 RNAi | Y41E3.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| xrn-1 RNAi | xrn-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| wah-1 RNAi | wah-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. RNAi against wah-1 started after the animal reaches the late L4 stage extends mean lifespan by 7-8% [22103665]. | Worm | +7 to +8 | — | — |
| vit-2 RNAi | vit-2 RNA interference extends mean lifespan by 21-24% [12845331]. | Worm | +21 to +24 | — | — |
| vit-1 RNAi | vit-1 RNAi animals have a mean lifespan that 103.3% of controls, but not significant different [12845331]. | Worm | — | — | — |
| vig-1 RNAi | vig-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| vab-1 RNAi | vab-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| l(3)neo18 RNAi | Under rich nutritional conditions lifespan of l(3)neo18 (alias CG9762) RNAi knockout animals is indistinguishable from wild-type, while upon DR, lifespan extension is diminished in males and females [19804760]. | Fly | — | — | — |
| CG11015 RNAi | Under rich nutritional conditions lifespan of CG11015 RNAi treated animals is indistinguishable from that of controls, while upon DR, lifespan extension is diminished in males and females [19804760]. | — | — | — | — |
| trap-4 RNAi | trap-4 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| tba-5 RNAi | tba-5 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| tag-341 RNAi | tag-341 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| tag-322 RNAi | tag-322 RNAi increases mean and maximum lifespan by 18 and 12%, respectively [19293945]. | Worm | +18 | — | +12 |
| T23D8.3 RNAi | T23D8.3 RNAi in the adulthood extends mean and maximum lifespan by 26% and 35, respectively [23144747]. | Worm | +25.7 | — | +34.7 |
| T08A11.2 RNAi | T08A11.2 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| T04A8.11 RNAi | T04A8.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| synaptobrevin RNAi | synaptobrevin RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| sur-2 RNAi | sur-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| srh-20 RNAi | srh-20 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| sos-1 RNAi | sos-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| Sod1 knockdown | Sod1 knockdown by RNAi blunts the lifespan extension by a high sugar-low protein diet, but not a low-calorie diet [22672579]. | Fly | — | — | — |
| snr-5 RNAi | snr-5 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
| snap-1 RNAi | snap-1 RNAi in the adulthood reduces mean and maximum lifespan by 40 and 50%, respectively [23144747]. | Worm | -39.9 | — | -50.0 |
GenAge
GenDR
