Denigma

BCY1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: BCY1
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Disruption in BCY1 by mutation results decreases mean and maximum replicative lifespan by 37 and 16% and is associated with increased PKA activity [8195187].

Mean: -37
Maximum: -16

References:
  • 8195187: Cloning and characterization of LAG1, a longevity-assurance gene in yeast.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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