Denigma

gdi-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: gdi-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNAi against gdi-1 started after the animal reaches the late L4 stage decreases mean lifespan by 6-7% [22103665]. gdi-1 RNAi decrease median lifespan by 34% in daf-2 mutants [18006689].

Mean: -6 to -7

References:
  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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