Denigma: Intervention

Cbs RNAi

Species: Fruit fly (Taxid: 7227)
Factor: Cbs
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Cbs RNAi partially abrogates increased lifespan by DR, but has no effect on fully fed animals. Cbs upregulation is required for increased lifespan under low-nutrient conditions. Response of male flies to DR is muted in comparison with females [21930912].

Aging Relevance Analysis/Source:

GenAge