MT-RNR2 | — | An single nucleotide polymorphism in MT-RNR2 is associated with longevity [18759861]. | Human |
PTK2 | — | PTK2 was found to be associated with longevity [24930376]. PTK2 was not found to be associated with longevity [24930376]. | Human |
PVRL2 | — | PVRL2 was found to be associated with longevity [24924924]. PVRL2 was not found to be associated with longevity [24924924]. | Human |
NOS2 | — | NOS2 was found to be associated with longevity [23572278]. | Human |
CYBA | — | — | Human |
CDKN2B | — | — | Human |
RAGE | — | — | Human |
TP53 | tumor protein p53 | A naturally occuring allele with decreased p53 activity has been assoicated with extended survival [15732191].TP53 was found to be associated with longevity [23125046]. TP53 was found to be associated with longevity [18256523]. TP53 was found to be associated with longevity [15621215]. TP53 was found to be associated with longevity [18256523]. TP53 was not found to be associated with longevity [15195682]. TP53 was not found to be associated with longevity [15621215]. | Human |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | BDH1 was found to be associated with longevity [22445811]. | Human |
NT5DC1 | 5'-nucleotidase domain containing 1 | NT5DC1 was found to be associated with longevity [22279548]. | Human |
MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 329 healthy individuals were examined for 2576A-->G (D919G) polymorphism in the MTR gene. Prevalence of the G-allele was significantly higher in the older than in the younger individuals. Separate analysis of female and male subjects revealed that the influence of the MTR genotype on male subjects became relevant at a younger age as opposed to female subjects suggesting a gender-dependent effect [16142417]. | Human |
AKAP10 | A kinase (PRKA) anchor protein 10 | Male (n= 4766) and female (n = 6202) divided into young (183-9 years) and old (60 years) groups were examined for polymorphisms. A polymorphism that results in an amino acid change from Ile to Val showed the strongest correlation with age. The Val variant was associated with a statistically significant decrease in the length of the electrocardiogram PR interval. An A to G polymorphism in the 3'UTR of D-AKAP2 showed a significant decrease of the G allele in the older sample of both genders. Additionally, the I646V polymorphism was found to be significantly different between young and old in both males and females [12646697]. | Human |
BAT5 | abhydrolase domain containing 16A | BAT5 was found to be associated with longevity [22279548]. | Human |
ACPL2 | acid phosphatase-like 2 | ACPL2 was found to be associated with longevity [22445811]. | Human |
ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | ADAMTS6 was found to be associated with longevity [22445811]. | Human |
C9orf94 | ADAMTS-like 1 | C9orf94 was found to be associated with longevity [22279548]. | Human |
ADA | adenosine deaminase | ADA was found to be associated with longevity [20174870]. ADA was found to be associated with longevity [21865054]. | Human |
ADARB1 | adenosine deaminase, RNA-specific, B1 | ADARB1 was found to be associated with longevity [20011587]. | Human |
ADARB2 | adenosine deaminase, RNA-specific, B2 | ADARB2 was found to be associated with longevity [20011587]. ADARB2 was not found to be associated with longevity [20011587]. | Human |
ADCY2 | adenylate cyclase 2 (brain) | ADCY2 was found to be associated with longevity [19641380]. | Human |
ADCY6 | adenylate cyclase 6 | ADCY6 was found to be associated with longevity [23020224]. | Human |
ADIPQO | adiponectin, C1Q and collagen domain containing | ADIPQO was not found to be associated with longevity [20201642]. ADIPQO was found to be associated with longevity [20201642]. | Human |
ADIPOQ10 | adiponectin, C1Q and collagen domain containing | ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [23339001]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was not found to be associated with longevity [18765803]. | Human |
ART3 | ADP-ribosyltransferase 3 | ART3 was found to be associated with longevity [22445811]. | Human |
ADRB2 | adrenergic, beta-2-, receptor, surface | ADRB2 was found to be associated with longevity [23020224]. ADRB2 was not found to be associated with longevity [23020224]. | Human |