|
Symbol: Sirt6 Entrez gene ID: 41254 Ensembl gene ID: FBgn0037802 Species: Fly (Taxid: 7227) Functional description: NAD(+)-dependent histone deacetylase that silences gene expression; NAD-dependent protein deacetylase (By similarity). May be involved in the regulation of life span. [UniProt] Observation: Decreased expression of Sirt6 by RNA interference causes lethality during development. Sirt6 silencing in neurons shortens mean lifespan by 20% [17159295]. Interventions: Assays: Organismal Lifespan Mean: -20 Classification: Type: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
Comment on This Data Unit