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Denigma
»
Lifespan
»
Variants
» Variant = rs13251813
o
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Admin
Ontology of Gerontology
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rs13251813
Polymorphism:
rs13251813
rs13251813
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
8p12
Factor:
- Symbol:
WRN
- Name:
Werner syndrome, RecQ helicase-like
- Entrez ID:
7486
- Ensembl ID:
ENSG00000165392
Factors:
WRN
Werner syndrome, RecQ helicase-like
(
7486
/
ENSG00000165392
)
Ethnicity:
Danish
Age of cases:
92-93 years old
Shorter lived allele:
G
Longer lived allele:
A
Finding:
Positive
Statistics
- Number of cases/controls:
1089 vs 736 (initial)
|
1613 vs 1104 (replication)
- Odds ratio:
1.84
- p-value:
0.0002 [0.0002]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
Illumina GoldenGate platform
Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Choice:
Curate_Emily
Created:
July 1, 2013, 10:47 a.m.
Updated:
Aug. 8, 2014, 1:05 p.m.
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