Symbol: Adcy5 Name: adenylate cyclase 5 Alias: AC5 Entrez gene ID: 224129 Ensembl gene ID: ENSMUSG00000022840 Species: Mouse (Taxid: 10090) Functional description: This is a membrane-bound, calcium-inhibitable adenylyl cyclase. [UniProt] Observation: Adcy5 knockout mice are to cardiac stress and have an increased median lifespan of 30% as well as an increased maximal lifespan of 12%. Further, they are also protected from age-related reduced bone density and susceptibility to fractures, and reduced cardiac function [17662940]. Interventions: Assays: Organismal Lifespan Median: +30 Maximum: +12 Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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