Symbol: nrx-1 Name: GLIoTactin (Drosophila neuroligin-like) homolog Entrez gene ID: 179503 Ensembl gene ID: C29A12.4 Species: Worm (Taxid: 6239) Functional description: Protein NRX-1; GLIoTactin (Drosophila neuroligin-like) homolog family member (nrx-1) [Source:RefSeq peptide;Acc:NP_505767] [Ensembl]; nrx-1 encodes the C. elegans ortholog of neurexins, presynaptic transmembrane neural adhesion molecules that contain extracellular laminin and EGF domains and play a critical role in synaptic development; genetic analyses suggest that nrx-1 may play a role in regulation of adult lifespan; nrx-1 expression is controlled by daf-2 and daf-16. [WormBase] Observation: Mutation reduced maximum lifespan by 40%. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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