Symbol: Pde5a Name: cGMP-specific 3',5'-cyclic phosphodiesterase Entrez gene ID: 171115 Ensembl gene ID: ENSRNOG00000014443 Species: Rat (Taxid: 10116) Observation: Pde5a is transcriptional downregulated in the cerebral cortex at the age 28 months under different longevity conditions such as under dietary restriction (DR) as well as in feeding switch regimens that result in extended lifespan, like early age switch to DR as well as the reverse switch under the influence of the DR-mimetic α-lipoic acid (i.e. DR switched to ad libitum+ lipoic acid) [Shona et al. 2013]. Assays: Organismal Lifespan Classification: Type: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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