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Symbol: unc-80 Name: UNCoordinated Entrez gene ID: 180374 Ensembl gene ID: F25C8.3 Species: Worm (Taxid: 6239) Functional description: Probable component of the nca-1 sodium channel complex, a cation channel that regulates neuronal activity by transmitting depolarization signals to synapses. Regulates the transition from slow to rapid forms of locomotion. Required for localization of nca-1 along axons and in non-synaptic regions. Contribute to endocytosis defects in synaptojanin mutants. Involved in the control of anasthetic response to halothane. [UniProt] Observation: The unc-80(e1069) allele has no significant effect on lifespan [9789046]. unc-80 mutant displays irregular movement [4366476] Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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