Symbol: RAD7 Name: RADiation sensitive 7 Entrez gene ID: 853512 Ensembl gene ID: YJR052W Species: Yeast (Taxid: 4932) Functional description: Rad7p; Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000003813] [Ensembl] Observation: Deletion of RAD7 has no effect on replicative lifespan in PSY316 [10207108]. Mutation in RAD7 results in decrease repair of the non-transcribed strand in rDNA [8604332]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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