Symbol: VPS36 Name: Vacuolar Protein Sortin 36 Alias: GRD12;VAC3;VPL11 Entrez gene ID: 851135 Ensembl gene ID: YLR417W Species: Yeast (Taxid: 4932) Functional description: Vps36p; Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome [Source:SGD;Acc:S000004409] [Ensembl] Observation: VPS36 deletion mutants have a chronological lifespan as long as wild type BY4741. Thus, Vps36 is not necessary for the starvation/extreme DR-dependent lifespan extension [20657825]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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