FRE6

Symbol: FRE6
Name: Ferric REductase 6
Entrez gene ID: 850675
Ensembl gene ID: YLL051C
Species: Yeast (Taxid: 4932)

Functional description:
Fre6p; Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels [Source:SGD;Acc:S000003974] [Ensembl]

Observation:

FRE6 deletion increases mean replicative lifespan by 14% and cancels out the lifespan extending effect of DR [22912585].



Interventions:
  • FRE6 deletion +14% -2%

  • Assays: Replicative Lifespan
    Mean: +13
    Maximum: -2

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • FRE2 (4932)
  • FRE3 (4932)
  • FRE6 (4932)
  • FRE4 (4932)
  • FRE5 (4932)
  • KLLA0E05897g (28985)
  • AGOS_ABR154C (33169)
  • GeneID:5050350 (148305)
  • GeneID:5051763 (148305)
  • GeneID:5049956 (148305)

  • Orthologs
  • FRE3 (4932)
  • FRE5 (4932)
  • FRE4 (4932)
  • FRE2 (4932)
  • FRE7 (4932)
  • FRE1 (4932)



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