YPK1

Symbol: YPK1
Name: Yeast Protein Kinase 1
Alias: SLI2
Entrez gene ID: 853733
Ensembl gene ID: YKL126W
Species: Yeast (Taxid: 4932)

Functional description:
Ypk1p; Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK [Source:SGD;Acc:S000001609] [Ensembl]

Observation:

Deletion of YPK1 decreases replicative lifespan by 20% in the alpha strain [18340043].



Interventions:
  • YPK1 deletion -20%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SGK2 (9606)
  • SGK2 (9598)
  • SGK2 (9913)
  • Sgk2 (10090)
  • Sgk2 (10116)
  • SGK2 (9031)
  • sgk2 (7955)
  • gad8 (4896)
  • YPK1 (4932)
  • YPK2 (4932)
  • KLLA0B12716g (28985)
  • AGOS_ABL028W (33169)
  • GeneID:2684754 (148305)
  • NCU07280 (5141)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit