Polymorphism: 1 SNPs, not specified
Location: Xq22.3
Factor:
- Symbol: IRS4
- Name: insulin receptor substrate 4
- Entrez ID: 8471
- Ensembl ID: ENSG00000133124
Factors:
IRS4
insulin receptor substrate 4
(
8471
/
ENSG00000133124
)
Ethnicity:
Caucasian
Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 145
Statistics
- Number of cases/controls: 330 vs 603;279 vs 797;383 vs 363 (initial)
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton
Reference:
19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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