Polymorphism: rs7896005
rs7896005
(
SNPedia |
23andMe
)
Location: 10q21.3
Factor:
- Symbol: SIRT1
- Name: sirtuin 1
- Entrez ID: 23411
- Ensembl ID: ENSG00000096717
Factors:
SIRT1
sirtuin 1
(
23411
/
ENSG00000096717
)
Ethnicity:
Caucasian
Age of cases: Range: 90-103
Shorter lived allele: A
Statistics
- Number of cases/controls: 224 vs 293 (initial)
| 170 vs 220 (replication)
- p-value:
0.0056
[0.0056]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology:
Reference:
21972126: Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity.
Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete