Polymorphism: K153R
Location: 2q32.2
Factor:
- Symbol: MSTN
- Name: myostatin
- Entrez ID: 2660
- Ensembl ID: ENSG00000138379
Factors:
MSTN
myostatin
(
2660
/
ENSG00000138379
)
Ethnicity:
Spaniard
Age of cases: Range : 100-111
Shorter lived allele: K
Longer lived allele: R
Statistics
- Number of cases/controls: 156 vs 384 (initial)
| 79 vs 316 (unelated Italian cohort) (replication)
- Odds ratio: 3.48
- p-value:
0.001
[0.001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
Reference:
23354683: Association of the K153R polymorphism in the myostatin gene and extreme longevity.
Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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