Polymorphism: rs429358, rs7412
rs429358,
(
SNPedia |
23andMe
)
rs7412
(
SNPedia |
23andMe
)
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
odds_ratio = 0.39 (1.89) (invalid literal for float(): 0.39 (1.89))
pvalue = 0.000156 (0.008414) (invalid literal for float(): 0.000156(0.008414))
Ethnicity:
American,
Caucasian
Age of cases: Mean 100,8
Shorter lived allele: e4
Longer lived allele: e2
Statistics
- Number of cases/controls: 653 (197 m, 456 f) vs non-mentioned (initial)
| 564 (92 m, 472 f) vs 564___(Franch Caucasians) (replication)
- p-value:
[0.000156 (0.008414)]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Sequenom's chip-based matrix-assisted laser desorption/ionization time-of-flight MS and RT-PCR
Reference:
14615589: Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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