Polymorphism: rs2072454, rs2293347, rs3807362, rs884225
rs2072454,
(
SNPedia |
23andMe
)
rs2293347,
(
SNPedia |
23andMe
)
rs3807362,
(
SNPedia |
23andMe
)
rs884225
(
SNPedia |
23andMe
)
Location: 7p12
Factor:
- Symbol: EGFR (for females)
- Name: epidermal growth factor receptor
- Entrez ID: 1956
- Ensembl ID: ENSG00000146648
Factors:
EGFR (for females)
epidermal growth factor receptor
(
1956
/
ENSG00000146648
)
Description:
Here were analyzed multiple genes and even SNP combinations, so it is very difficult to make it as a short report. There were 2 types of data for SNPs: as I understood primary and after inheritance fitting modeling. I`ve depicted first one. Also there is no clear description of alleles.
Ethnicity:
Korean
Age of cases: Mean age 90
Longer lived allele: CGCA
Statistics
- Number of cases/controls: 137 vs 213 (initial)
- Odds ratio: 4.11
- p-value:
0.003
[0.003]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Sentrix Array Matrices
Reference:
19641380: Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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