| 531 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✘ | — | — | Mutation | — | — | — | 535.0 | 570.0 | 898.0 | 50 |
| 530 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✔ | — | — | Mutation | — | — | — | 388.0 | 297.0 | 814.0 | 50 |
| 85 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✘ | white1118 | da>EPCG6783 | — | — | — | — | 46.0 | 58.0 | 72.0 | — |
| 139 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1 | Dietary Restriction | — | 30.0 | — | 42.9 | 50.0 | 64.0 | 20 |
| 140 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | Dietary Restriction | — | 30.0 | — | 45.3 | 48.0 | 67.0 | 20 |
| 210 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 45.0 | 45.0 | 75.0 | 31 |
| 138 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | — | — | 30.0 | — | 46.0 | 44.0 | 78.0 | 20 |
| 214 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 44.0 | 43.5 | 76.0 | 40 |
| 215 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | — | — | — | — | 42.0 | 43.0 | 75.0 | 36 |
| 525 | Fig. 3. Animal survival and growth | ✘ | Wistar | — | Mutation | — | — | — | 62.0 | 42.0 | 66.0 | 6 |
| 87 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✘ | white1118 | da>EPCG13890 | — | — | — | — | 35.0 | 42.0 | 60.0 | — |
| 132 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | afg3;fob1 | — | — | 30.0 | — | 38.3 | 40.0 | 60.0 | 40 |
| 216 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | Dietary Restriction | — | — | — | 40.0 | 40.0 | 64.0 | 38 |
| 197 | Figure 2 | Vacuolar acidity is reduced in ageing cells and regulates mitochondrial function and lifespan. | ✘ | S288c | VMA1(OE) | — | — | — | — | 39.0 | 39.0 | 80.0 | 56 |
| 194 | Figure 3 | Reduced vacuolar acidity causes mitochondrial dysfunction by disrupting amino acid homeostasis. | ✘ | S288c | AVT1(OE) | — | — | — | — | 37.0 | 37.0 | 62.0 | 32 |
| 147 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | rpl20b | — | — | 30.0 | — | 33.8 | 36.0 | 60.0 | 59 |
| 131 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✔ | — | fob1 | — | — | 30.0 | — | 32.7 | 35.0 | 52.0 | 39 |
| 137 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✔ | — | sir2;fob1 | — | — | 30.0 | — | 30.8 | 34.0 | 46.0 | 20 |
| 222 | Figure 3. Increased life span of cardiotrophin 1 (CT-1)–null mice. | ✘ | C57BL6 | CT-1(null) | — | — | — | — | — | 33.0 | — | 24 |
| 162 | Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains | ✘ | — | idh1 | — | — | 30.0 | — | 32.6 | 33.0 | 60.0 | 304 |
| 160 | Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses | ✘ | — | rad52 | — | — | 30.0 | — | 10.8 | 33.0 | 10.0 | 130 |
| 218 | Supplementary Figure 3. Phenotypes of VPH2 overexpression mimic those observed with VMA1 overexpression. | ✘ | S288c | VPH2(OE) | — | — | — | — | 32.0 | 32.5 | 67.0 | 52 |
| 186 | Figure 5: Hac1-independent resistance to tunicamycin in afg3∆ and rpl20bΔ cells | ✘ | — | afg3;hac1 | — | — | 30.0 | — | 30.7 | 32.0 | 50.0 | 40 |
| 83 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✔ | white1118 | da/+ | — | — | — | — | 26.0 | 32.0 | 64.0 | — |
| 148 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | afg3rpl20b | — | — | 30.0 | — | 30.3 | 32.0 | 52.0 | 40 |
