| 216 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | Dietary Restriction | — | — | — | 40.0 | 40.0 | 64.0 | 38 |
| 214 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 44.0 | 43.5 | 76.0 | 40 |
| 212 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | vma2 | Dietary Restriction | — | — | — | 2.0 | 2.0 | 12.0 | 52 |
| 210 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 45.0 | 45.0 | 75.0 | 31 |
| 140 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | Dietary Restriction | — | 30.0 | — | 45.3 | 48.0 | 67.0 | 20 |
| 139 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1 | Dietary Restriction | — | 30.0 | — | 42.9 | 50.0 | 64.0 | 20 |
| 573 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✔ | — | WT | Mutation | — | — | — | 17.6 | — | 27.0 | — |
| 531 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✘ | — | — | Mutation | — | — | — | 535.0 | 570.0 | 898.0 | 50 |
| 530 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✔ | — | — | Mutation | — | — | — | 388.0 | 297.0 | 814.0 | 50 |
| 529 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✘ | — | — | Mutation | — | — | — | 285.0 | — | 340.0 | 32 |
| 528 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✔ | — | — | Mutation | — | — | — | 264.0 | — | 311.0 | 34 |
| 525 | Fig. 3. Animal survival and growth | ✘ | Wistar | — | Mutation | — | — | — | 62.0 | 42.0 | 66.0 | 6 |
| 524 | Fig. 3. Animal survival and growth | ✘ | Wistar | — | Mutation | — | — | — | 41.0 | 26.0 | 58.0 | 6 |
| 523 | Fig. 3. Animal survival and growth | ✔ | Wistar | — | Mutation | — | — | — | 29.0 | 22.0 | 38.0 | 6 |
| 577 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✘ | — | WT | RNA Interference | frh-1 IV(RNAi) | — | — | 20.9 | — | 37.0 | 149 |
| 576 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✘ | — | WT | RNA Interference | frh-1 III(RNAi) | — | — | 16.7 | — | 27.0 | 130 |
| 575 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✘ | — | WT | RNA Interference | frh-1 II(RNAi) | — | — | 17.2 | — | 27.0 | 140 |
| 574 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✘ | — | WT | RNA Interference | frh-1 I(RNAi) | — | — | 18.3 | — | 27.0 | 130 |
| 516 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | mir-71(n4115) | RNA Interference | cdc-25.1(RNAi) | 20.0 | — | 11.0 | — | 14.0 | — |
| 515 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | wild-type | RNA Interference | cdc-25.1(RNAi) | 20.0 | — | 22.0 | — | 27.0 | — |
| 512 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | mir-71(n4115) | RNA Interference | daf-16(RNAi) | 20.0 | — | 10.0 | — | 13.0 | — |
| 511 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | wild-type | RNA Interference | daf-16(RNAi) | 20.0 | — | 14.0 | — | 19.0 | — |
| 507 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | wild-type | RNA Interference | daf-2(RNAi) | 20.0 | — | 33.0 | — | 40.0 | — |
| 504 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | mir-239(nDf62) | RNA Interference | daf-2(RNAi) | 20.0 | — | 26.0 | — | 33.0 | — |
| 503 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | wild-type | RNA Interference | daf-2(RNAi) | 20.0 | — | 29.0 | — | 34.0 | — |
