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Denigma
»
Lifespan
>
Interventions
>
rb mutation
o
Interventions
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Mouse Lifespan Experiments
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rb mutation
Species:
Fruit fly
(Taxid:
7227
)
Factor
:
rb
Manipulation:
Loss-of-Function
,
Mutation
Effect:
Loss-of-function mutation reduces mean lifespan by 33 and maximum lifespan by 22% [
17435236
].
Mean:
-33
Maximum:
-22
References:
17435236: Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.
Aging Relevance Analysis/Source:
GenAge
GenDR
Comparisons:
ruby vs. Canton-S ( 25°C male ) : -32.6(mean) -22.1(max) 0.0001(p-value)
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