hk mutation

Species: Fruit fly (Taxid: 7227)
Factor: hk
Manipulation: Loss-of-Function, Mutation
Effect:

Loss of function mutation in hk decreases mean lifespan by 58 - 60% and maximum lifespan by 15 - 47% [17435236].

Mean: -58 to -60
Maximum: -15 to -47

References:
  • 17435236: Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • hook/hook vs. Canton-S ( 25°C male ) : -60.0(mean) -14.7(max) <0.0001(p-value)
  • hook vs. Canton-S ( 25°C male ) : -57.6(mean) -47.1(max) <0.0001(p-value)



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