Collaborations

Collaboration is working together in an intellectual endeavor to achieve a common goal. o

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  • project Organizations members People Description
    in situ Regeneration 1 2 Wuttke; Zamani :Abstract: As we are young everything regenerates perfectly. In fact, our body harbors the plan to reconstruct itself from scratch which is localized in the nucleus of each of our body cells. However, as we grow up our regenerative capacities decre...
    Pentose Phosphate Pathway 2 3 Magalhaes; Wuttke; Tang The pentose phosphate pathway chiefly generates reduction equivalents in the form of NADPH: 3 G6P + 6 NADPH+ + 3 H2O = 6 NADPH + 6 H+ + 3 CO2 + 2 F6P + GAP 6 equivalents of NADPH is quite a lot for just three sugars. NADPH might scavenge ROS. ...
    Tissue-Specific DR-Effects 2 4 Kapahi; Magalhaes; Wuttke; Li :Abstract: A restricted diet without malnutrition highly effectively counteracts ageing in several species and extends robustly their lifespan. How lifespan is extended remains enigmatic. We utilized tissue-specific gene expression data in *Droso...
    Circadian Rhythm 2 4 Kapahi; Magalhaes; Wuttke; Katewa Most animals have rest/activity/rhythms that are powered by an endogenous timing mechanism, the circadian system. With aging the rhythm becomes weaker [23223368]. Middle aged flies exhibit reduced activity level in comparison with young controls. ...
    Circadian Clock Controls Ageing 2 3 Magalhaes; Wuttke; Wood :Abstract: Dietary restriction without malnutrition delays ageing and extends lifespan, but the molecular mechanism is still unknown. Ageing gene expression changes originate from development and growth cessation, are modulated by diet, and manip...
    Collaborative Knowledge-Management 1 2 Kulaga; Wuttke We will establish **new kind of collaboration models** between people (including Researches) and in **Graph representation of knowledge**. ``Collaboration and knowledge-management websystems`` are the clue that **increases collective intelligence*...
    Continuous Longevity Meeting 3 4 Debonneuil; Wuttke; Singh; Maidano The **Worldwide Continuous Longevity Meeting** is a continuous ``discussion channel`` where anyone can decide to launch global collaborative presentations. The inventor **Edouard Debonneuil** proposed to incorporate it as an organ of the ``Internatio...
    Encouraging Initiative 1 2 Wuttke; Coernette A merit earning system build on top of the Achievements, that gives Researchers, Developers and Artists as well as other people the recognition and respect for their contribution and work need to be established. Such a system that awards merit for go...
    Semantic Web Against Aging 1 7 Kulaga; Medvedev; Wuttke; Repnikov; Borisoglebsky; Orlovs; Zimin .. contents:: **Contents** Authors : Daniel Wutske (Hevok), Anton Kulaga (antonkulaga), Dmitry Borisoglebsky Preface ======= Let us start from the original description of Denigma Project and then move forward. “By integrating all...
    Global Computing Initiative 1 5 Kulaga; Wuttke; Borisoglebsky; Brown; Bartko | **Global** GCI | **Computing** | **Initiative** The Global Computing Initiative (GCI) are Developers dedicated in the development of computational technologies that facilitate the advancement of human collective knowledge and support anti-Agin...
    Human Experimental Aging Biology 2 3 Debonneuil; Wuttke; Watson The system of clinical trials in Western countries has been bogged down by high costs, red tape, and governmental restrictions to the point that within 10 years the engine of innovation in biotechnology will die [22378269]. In order to prevent thi...
    Microarray Game 3 3 Shytikov; Wuttke; Tang There are many possibilities to analyze molecular Signatures. They can be compared to each other, meta-signature via Meta-Analysis can be derived, functional enriched terms can be assessed as well as Lifespan Factors identified. It is possible to ...
    Aging Reprogramming 0 3 Stolzing; Wuttke; Johnson :Abstract: Ectopic expression of defined pluripotence-associated Factors reprograms adult somatic cells back to an Embryonic Stem Cell-like state. During this process the phenoytpic characteristics of Aging are also reverted. Cells can even be di...
    miRNAs Control Aging 3 8 Schaum; Yivanoudi; Keller; Pate; Wuttke; Kumar; Conley; Swanson :Abstract: Gene silencing via RNA interference is mediated by microRNAs which are major controller of developmental processes and its plasticity conferred by diet. The function of specific miRNAs is going beyond the developmental period and extends...
    Information Theory 2 3 Stambler; Wuttke; Blokh Information theory is a field of applied mathematics, engineering and computer science that measures information. It originates from the finding of the fundamental limits on signal processing operations, such as compressing data, and on reliable s...
    Age In Vivo 2 7 Kulaga; Wuttke; AgeVivo; Logic; Mind; cryonicsculture; Horusavatar *in vivo* (Latin for ``within living``) is experimentations that **utilizes whole living organisms**. Age *in vivo* is ``do it yourself`` **Biology on Aging**. The goal is to bring in more people interested in Aging. Hence, it is primarily of prom...
    Graph Visualization 3 7 Stambler; Kulaga; Wuttke; Nishry; Mind; Atraylen; Horusavatar **Data on Aging** need to be **visualized** with an ``interactive`` and ``intuitive interface`` that enables ``collaborative reverse-engineering`` of the Aging process. It shall be a popular and interactive way of to convey a basic understanding of t...
    Non-Programmed Aging Hypotheses 1 2 Wuttke; Libertini ############################### Non-Programmed Aging Hypotheses ############################### ========================================= Tenable Scientific Theories or old Dogmas ========================================= :Abstract: Knowing t...
    Longevity Variant Database 3 6 Schaum; Wuttke; Adams; Betts-Lacroix; Juan; Fortney ########################## Longevity Variant Database ########################## :Journal: Nucleic Acid Research :Deadline: 25th August 2013 :Abstract: We are constructing the most comprehensive database on genetic variants associated with longe...
    Denigma 5 9 Fuellen; Magalhaes; Debonneuil; Kulaga; Wuttke; Adams; Borisoglebsky; Fortney; Hall Denigma is the digital Enigma destined to decipher biological phenomena. All information of an organism is encoded in its genome and can be decrypted via the combined effort of humans and machines. For this, Denigma was build for. Specifically, Deni...
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