Authors: Sinclair D; Verdin E
Abstract: Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.
Journal: Cell reports Volume: 2 Issue: 6 Pages: 1473-4 Date: Jan. 1, 2013 PMID: 23273894 |
Sinclair D, Verdin E (2012) The longevity of sirtuins. Cell reports 2: 1473-4.
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