Polymorphism: rs11575134
rs11575134 ( SNPedia | 23andMe )

Location: 2q33-q36

Factor:
- Symbol: IGFBP5
- Name: insulin-like growth factor binding protein 5
- Entrez ID: 3488
- Ensembl ID: ENSG00000115461

Factors:
  • IGFBP5 insulin-like growth factor binding protein 5 ( 3488 / ENSG00000115461 )

  • Ethnicity: Caucasian
    Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 137

    Statistics
    - Number of cases/controls: 322 vs 603;279 vs 797;383 vs 363 (initial)
    - Odds ratio: 1.07
    - p-value: 0.36 [0.36]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton

    Reference:
    19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

    Edit (Admin) | Delete