Polymorphism: rs6670
rs6670 ( SNPedia | 23andMe )

Location: 7p13-p12

Factor:
- Symbol: IGFBP3
- Name: insulin-like growth factor binding protein 3
- Entrez ID: 3486
- Ensembl ID: ENSG00000146674

Factors:
  • IGFBP3 insulin-like growth factor binding protein 3 ( 3486 / ENSG00000146674 )

  • Ethnicity: Caucasian
    Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 134

    Statistics
    - Number of cases/controls: 319 vs 603;279 vs 797;383 vs 363 (initial)
    - Odds ratio: 1.02
    - p-value: 0.75 [0.75]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton

    Reference:
    19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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